Employee Management Plan

Running head: EMPLOYEE PORTFOLIO: MANAGEMENT PLAN Employee Portfolio: Management Plan MGT/311 Organizational Development University of Phoenix Riordan Manufacturing has implemented a management plan that will assess employees’ characteristics. By assessing their characteristics, the organization will know how to use their characteristics to make the organization more successful. The company has asked three employees to complete self-assessments about job satisfaction.The assessments will ultimately allow management to discover characteristics of the employees and determine how these characteristics will affect Riordan Manufacturing in the future. Self-assessments give an employee the opportunity to provide a narrative description of their major accomplishments, job satisfaction, emotional influence and how they make decisions related to their performance. In a self? assessment, the employee can describe their major contributions and how they accomplished or did not accomplish their performance expectations.After a thorough analysis of the self-assessments, additional recommendations will be presented to assist Riordan Manufacturing gain a better perspective on the management and motivation that these employees will need in order to succeed. The participants in the Riordan Manufacturing self-assessments were Catrina Toth, Kyle Rogers, and Paul Holliday. The following self-assessments were administered to the employees: How Satisfied Am I with My Job, Am I Engaged, How Are You Feeling Right Now, What’s My Affect Intensity, What’s My Emotional Intelligence Score, and Am I A Deliberate Decision Maker?Management will use these assessments to identify the areas in which they scored high and low and create a plan based on the areas that mostly need more engagement. Catrina’s self-assessments indicate a job satisfaction rating at an average. She is satisfied with her job but not really engaged, is a deliberate decision maker, and exhibits po sitive emotions. Kyle has an above average rating in most areas; he is very satisfied with his job and is engaged in his work, exhibits an average score on deliberate decision-making and demonstrates positive emotions.Paul demonstrates a high score in job satisfaction, is a deliberate decision maker and also exhibits positive emotions on his self-assessments. The efficiency of the company is directly affected when employees are satisfied with their job and position held. An employee with a high level of job satisfaction feels more positive about his or her job and will continue to be a productive member of the company. Job Satisfaction Job satisfaction is the general attitude one holds about a job, which can dramatically affect the effectiveness and efficiency of the organization† (Robbins & Judge, 2011). Companies with satisfied employees tend to reduce the levels of absenteeism and turnover rate. Employees with low levels of job satisfaction experience negative attitudes abo ut their jobs, tend to have a high absenteeism rates, leave the organization, or engage in deviant behaviors that negatively affect the organization and other employees.The self-assessment results reveal that employees at Riordan Manufacturing exhibit positive behaviors influencing other employees in the workplace. Employee Engagement The employees’ engagement indicates their involvement and enthusiasm for their work (Robbins & Judge, 2011). All three of the self-assessed employees are highly satisfied with their jobs, are committed to their responsibilities, and motivated. Dedicated employees commit more time to their work, are a positive influence on others, and perform at higher levels than expected.Self-Assessment Recommendations Management at Riordan Manufacturing recommends additional assessments to conclude what is their job satisfaction level. Understanding these factors would describe a positive feeling about a job. It is important to understand what provides positiv e feelings and low-level negative feelings. Also management recommends more job involvement because this would enhance the level of attitude toward the assigned tasks and duties.It is important to be involved because management can identify strengths and show that company cares about the kind of work employees do. The recommendation of additional assessments will provide both the employees and managers with additional information on each personality to implement better managerial techniques. Based on those results, managers will develop management plans to encourage and mentor employee success. References Robbins, S. P. , & Judge, T. A. (2011). Organizational behavior (14th ed. ). Upper Saddle River, NJ: Pearson/Prentice Hall.

Biblical Servant Leadership

Jesus set a great model to us. Yet He is the master, the greatest?he has the power and the ability to stand on top of the crowd but He Is also the least and the lowest to be able to wash the feet to human beings. I think the most challenged but precious part is the second one especially if you are a leader. That's why called â€Å"Servant† leader. Yet serving others can be tough; expending energies and time in the interest of others can be exhausting. I believe as a Christian we all experience that spent lots of time accompany with non-believers but then captioned later on or felt being used.Yet we felt hurt and trust me, I DO. However, every time when I look through what Jesus had suffered, the betrayal, I know there Is nothing to compare and I also be comforted from Him knowing He Is taking in charge; thereby, I become more mature slowly by slowly. I do believe the more you emulate from Him, the more you know how to be a real leader who stand firmly in this spiritual and sec ular world. Does one leadership model appeal to you more than the others? If yes, why? Yes.In y point of view, Richard Arden gives the most understandable and the easiest concept when we talk about how to be a servant leader. The whole point of being a servant leader is that you know God is the Lord. In other words, He is the first of the first. If there Is not God involves in then there will be just talking about the secular leadership. Therefore, God holds all the authority not a person (leader) who has this right from his own. Secondly, as a servant leader you must know you are the chosen partner from God to lead a group of people or a task to fulfill God's own wills.Therefore, leadership Is a partnership between the leader and God the almighty. Thirdly, Jesus has given the best example of being the first is being the last. He is the first, the almighty and the only one without the sin but bore the mocks from sinners and crucified for the rest. Another example, He, the first, had washed the feet for the followers as a servant (the least) with a humble heart. The real leader is not the one who can only be on top but often the one who humble himself to do the lowliest thing In the group.Fourthly, leadership Is a fullness of concept and action. A servant leader must do and think It completely from Inside out. You cannot hide the arrogance in your heart and do all the good things to others and say you are the loyal servant of God. There is no hidden thought that can't be seen from our Lord. Fifthly, leadership is the spiritual gift from God because not anyone can be given this empowerment. Therefore, the great power comes the great responsibility. At last, a true servant leader should be clear that all the followers who be authorized to lead

Health and Safety Essay Example | Topics and Well Written Essays - 2250 words

Health and Safety - Essay Example The manager is now faced with a tough problem and that is to find means to save the image of the product and the company. This will cause a disruption in the manager’s planned routine and he will try to curtail losses as much as possible. Furthermore, the manager will try to gain back the confidence people has in his brand and his company and will therefore invest his time, energy and resources to retain the company’s market share. Hence, it is evident that safety plays a vital role in a manager’s job. Safety ensures the well being of a business in all aspects. Be it the manufacturing process, work place environment, food and beverages, occupational hazards or the environment in which business takes place. Safety is important for the efficient running of these processes and for the welfare of the people involved in these processes. For a business to prosper all business functions should work together and perform efficiently. Therefore, safety issues need to be considered right across the organizational domain starting from production and going up to shipment and delivery. For this reason most companies have developed standards for safety in their work domain and ensure that safety standards are always met. According to the WHO, food and waterborne diseases are the leading causes of illness and death in less developed countries, killing approximately  2.2 million people annually, an estimated 1.8 million of whom are children Therefore, the recent trends in global food production, processing, distribution and preparation are creating an increasing demand for food safety to ensure a safer global food supply (WHO). Even in the developed countries food safety has become a major concern. Food safety needs to be ensured in restaurants as well as homes to prevent people from catching food borne diseases. The WHO has identified five ways to ensure

INCLUSION AND MEETING SPECIAL EDUCATION NEEDS Essay

INCLUSION AND MEETING SPECIAL EDUCATION NEEDS - Essay Example The main intention of social inclusion is to eradicate favoritism and support social unity meant to boost peaceful coexistence within a community. One main area of social inclusion is to develop a framework that focuses on improving educational attainment among all children within the community regardless of their individual difference and families (Frederick and Cline, 2009, p.34). Yee and Dumbrill (2003, p. 23) noted that, by teachers removing barriers to educational engagement and educational achievement, children would be able to take part in educational activities, and succeed in all aspects of education within the school community. Social inclusion within the school setting in closely linked to school leadership style that develops a justice system within the school context (Keith and Maloney, 2005, p.98). School social inclusion can be seen as an attempt to integrate all aspect of the schools through various social groups established by the school administration. It may be described as how different individuals within the school context are recognized and treated with respect irrespective their backgrounds (Power and Wilson, 2000, p.66). Social inclusion in education is a course of action that aims at removing barriers to acquiring educational needs, and develops their aptitudes. These aptitudes could be theoretic, realistic, social in nature, and cultural (Power and Wilson, 2000, p.66). Social inclusion in education presents a well-planned education system that caters for different individuals in different backgrounds. These expanded requirements should be prepared and directed locally (Power and Wilson, 2000, p.66). A study conducted by Power and Wilson (2000, p. 89) indicated that implementing the concept of social inclusion within a school can be channeling in two aspects. These are economic aspect and the cultural aspect. Looking

Contemporary Developments in Business and Management in Tesco Essay

Contemporary Developments in Business and Management in Tesco - Essay Example TESCO is one of the leading international retailers in the world. It was started in the mid of 1920s with the trading name TESCO. Since then the company has slowly expanded and marked its presence in different markets and sectors (TESCO) . The growth strategy of the company is a long-term strategy based on four key parts: growth in the Core UK business to expand by growing internationally to be as strong in non-food as in food and to follow customers into new retailing services. Knowing this little information about the company, the environmental analysis of the company is done and presented in the forthcoming paragraphs. PESTLE analysis is a useful tool for understanding the "big picture" of the environment, in which you are operating, and the opportunities and threats that lie within it. By understanding the environment in which you operate (external to your company or department), you can take advantage of the opportunities and minimize the threats. (RAPIDBI) Specifically the PEST or PESTLE analysis is a useful tool for understanding risks associated with market growth or decline, and as such the position, potential and direction for a business or organization. Political Environment: Political forces influence the legislations and government rules and regulations under which the firm operates. Every company faces political constraints in the form of antitrust laws, fair trade decisions, and tax programs, minimum usage legislations, pollution and pricing policies, administrative activities and many other actions, aimed at protecting the consumers and the local environment. In 2001, The Department of Trade and Industry (DTI) introduced a Supermarkets' Code of Practice to regulate trading relationships between the four largest UK supermarkets and their suppliers. Tesco is a signatory to the Code and has met its obligations for implementing the Code. The company is committed to maintaining strong mutually advantageous relationships with its suppliers. Economic Environment: Economic factors clearly indicate the nature and direction of the economy in which a firm operates. Every market is unique and consumption patterns change along with the wealth of the consumers in various market segments. For strategic planning all the economic trends at national and international levels have to be considered. Tesco makes a significant contribution to economic activity in all the places in which it operates. Every week over 400,000 staff serves over 30 million customers in 13 countries. The company has to its credit a track record of providing value for customers, creating jobs and training, providing opportunities for suppliers and regenerating deprived areas. The business relationship of Tesco is with nearly 2,000 own-brand primary suppliers in 98 countries. Social Environment: The social environment is an important factor as changes in the values, beliefs, attitudes, opinions and lifestyles in society create potential opportunities for an organization. For

Executive Briefing Essay Example | Topics and Well Written Essays - 1750 words

Executive Briefing - Essay Example Strategic planning is about what the organization does; whom it does it to; and how it excels. This paper seeks to analyze the importance of strategic planning to homeland security organizations. Strategic planning, in most organizations, is basically a process used to determine where the organization is headed to over a year or more. Strategic planning therefore includes the mastery of the organization’s mission, vision, strategies, and values (Ahrenfelt, 2006). Strategic planning is therefore important for homeland security organizations in that the process will enable them understand, where they are currently with their services, the people they are serving, where they want to be in the near future, and strategies and courses of action they need to get to the destination of their choice. According to strategic planning, various approaches can be used to achieve components of strategic management. However, to homeland security organizations, it will be vital for them to appl y approaches such as: the Situation Target Proposal Approach, which evaluates the currently existing condition and how it resulted, defines objectives and goals of the organization, and maps the most probable path or route to achieving those objectives and goals; and the Draw See Think Plan Approach, which defines the desired end state or the ideal organization’s image, defines the situation today and determines the existing gap from the idea and the reason for that gap, determine the specific courses of action that must be undertaken in order to seal the gap existing between the ideal state and the current condition, and plans the required resources that will facilitate the execution of strategy activities (Donald, 2004). These approaches describe strategic planning importance to homeland security organizations. Through strategic planning, the homeland security organization is able to train its employees and take positive steps towards establishing a department wide approach which is effective in executing its duties. Strategic planning is important to homeland security organizations, because it helps the department to address the challenge of cultural change and transformation, and aid it ensuring that the workforce possesses the skills and knowledge that is required to respond effectively to both the current and future threats to the organization. Some of the actions already taken by the homeland security organization because of the importance of strategic planning include; issuing the strategic plan for training, establishing training groups and councils in order to increase communication across the components, and providing directly training for particular departmental need (Fridson, 2001). However, without effective strategic planning, homeland security organizations are likely to be impeded by several challenges. This is because without strategic planning, there would be lack of compatible or common information management systems as well as a tra ining terminology commonly understood, hence making sharing of information on training difficult (Donald, 2004). Lack of strategic planning will also lead to unclear relationships of accountability and authority between the components of organization and the office of the human capital. In the absence of strategic planning, planning by the homeland security organization will be insufficiently detailed in ensuring coordination and effective implementation of training efforts. Strategic planning is also important to the homeland secu

Speech Essay Example | Topics and Well Written Essays - 1250 words

Speech - Essay Example Education is a fundamental right entrenched in the constitution of many nations. Generally, education defines an avenue through which accumulated knowledge, cultures, values, technical skills, and customs passes from one generation to another through a well-defined system under the law. It takes place in an institution of learning famously known as a school following a system known as a curriculum. In fact, we acquire education through training, learning, research, and experimentations. The process of acquiring education is expensive and thus requires funding either from the government or from individuals. Moreover, there are different types of education that take place in variant levels of education. Nevertheless, the education process has no end with more education advancements becoming requisite with the ever-increasing societal needs. We refer to education givers as tutors, lecturers, or teachers depending on the level and type of education they are offering. However, at any leve l, there is assessment inform of examinations that measures success in education. Most significant, is the impact of education in the society where it ultimately helps individuals make the right decisions. It is arguably true that education has undergone many revolutions and restructuring in the recent times but its uniqueness and impact remains unraveled. The revolution has brought about different categories of educations that apply in variant countries. In general, we have three types of education that include formal education, adult education, and special education. Formal education is the streamlined type of education that encompasses the process of getting primary education, higher education and full time professional training as well as extra-curricular activities. It is the most fundamental type of education that is relevantly applicable to students seeking professional careers. The top cream of formal education includes university professors with a PhD and requisite

Essay NO. U2 P2 Example | Topics and Well Written Essays - 1000 words

NO. U2 P2 - Essay Example These can be understood as part of the employability skills. For instance, the most required personal skills are flexibility and adaptability which means that employees are able to generate new ideas while also showing openness to different concepts presented to them. Moreover, people who have the ability of working independently are preferred most. An individual’s professionalism increases when he/she is able to act positively while maintaining all the required codes of ethics. Energy and positive attitude further helps in achieving difficult tasks. However, it should also be reflected in one’s personality, outlook, manners etc. Communication skills have very high significance when it comes to employability because an employee who does not have good verbal and written communication skills then he cannot work efficiently. These include the ability to maintain eye contact and clear pronunciation of words. Following are the most important communication skills: Open mindedness: Newly hired employees must have open mindedness towards their co-workers, managers and sub-ordinates. This will help them in generating positive emotions while respecting one another to a greater extent. It is usually helpful in outlining the skills, education and trainings required to perform by a job candidate. It helps employers to distinguish individuals on the basis of their application forms whereas employees also evaluate different work opportunities through the job description. It consists of following sub-sections: Attributes and requirements: In order to fulfill the organizational requirements employers outline certain attributes which they want to see in potential candidates. For instance, if the job requires machinery work then the specific machines to be used by the employee should be mentioned here. It also includes details about the work environment. Evaluation and

UK Mobile Phone Segment Coursework Example | Topics and Well Written Essays - 4750 words

UK Mobile Phone Segment - Coursework Example This essay discusses that the shifts in the segment have been heavily influence and impacted by the development and popularity of smart phones that have changed the dynamics of the mobile phone segment from a portable communications alternative from landlines, to one that includes a social (text messaging, social networking), bill pay and organisational devices with exceptional on the go email connectivity, multifunctional medium whereby smart phones resemble miniature computers in terms of capabilities. The nuisances of the industry that are noteworthy is that in 2010 mobile phone connections, meaning calls made, increased with smart phones, SMS messaging and tablet SIM cards contributing 80 percent to that growth. The near saturation of the market in terms of mobile phone placements means that price and package bundling competition has heated up as the means to retain, and gain new subscribers. In equating the industry sector a PEST Analysis provides insight regarding the environme nt mobile telecom companies in the UK operate under. It aids in understanding the relevant trends by looking at the Political, Economic, Social and Technological factors. Under a PEST Analysis, a scan of the overall general industry environment from a long-term perspective aids in understanding broad based trends. In ascertaining the overall Political climate with regard to regulations in the United Kingdom as represented by the mobile telecom sector, the arena has been stabile. ... mobile messaging as a result of smart phones and the trending toward a younger subscriber profile represented key factors in the revenue changes and changing face of the UK mobile telecom sector. Figure 4 – Mobile Messaging Volumes (Ofcom, 2011, p. 282) Â   As indicated, the growth in popularity of smart phones was responsible for the above: Â   Figure 5 – UK Smart Phone Sales (Ofcom, 2008, p. 210) Â   The shift from landlines to mobile services took off in 1998 as shown by the following: Â   Figure 6 – UK Telecom Industry Retail Revenue (Ofcom, 2008, p. 198) Â   As a result of heightened competition, mobile telecom service cost to subscribers has converged to the point where the cost is comparable to fixed line costs: Â   Figure 7 – Comparison of Average Fixed and Mobile Voice Call Services (Ofcom, 2011, p. 302) Â   The preceding figures reinforce the point that the industry has become price sensitive, thus explaining the rationale behind the merge r that created Everything Everywhere. Â   Market Structure In equating the industry sector a PEST Analysis provides insight regarding the environment mobile telecom companies in the UK operate under. It aids in understanding the relevant trends by looking at the Political, Economic, Social and Technological factors (marketingteacher.com, 2009). Under a PEST Analysis, a scan of the overall general industry environment from a long-term perspective aids in understanding broad based trends (netMBA, 2009). In ascertaining the overall Political climate with regard to regulations in the United Kingdom as represented by the mobile telecom sector, the arena has been stabile. The actions of consumer groups have raised issues represented by the method of calculating call termination procedures they state are overcharging consumers

Aristotles virtue ethics Essay Example | Topics and Well Written Essays - 250 words

Aristotles virtue ethics - Essay Example The main goal of his virtue theory is to reach out the excellence (virtue) in self-performance, i.e. achieving happiness throughout life. As I see, Aristotle’s virtue theory is helpful for contemporary individuals living in a highly demoralized society. The question is that to what extent each individual normally sees the state of happiness. Definitely, it depends on likes and dislikes people have. However, to separate goodness from evil is really vital for sound-minded individuals. Thus, I feel that this theory fits into contemporary requirements of the mankind. Therefore, I have come to such a conclusion that Aristotle’s virtue theory is a predominant source to nurture virtues of goodness among individuals. The society and different communities within it will have an opportunity to improve due to being loyal to the virtues theory as an elementary instruction to reach out the social equilibrium. This tendency should lead people in an upward

Library an Internet Essay Example for Free

Library an Internet Essay The internet and the library , both are the considered to be a big depository of information .Library can be defined as [1]â€Å"A collection of literary documents or records kept for reference or borrowing† While Internet is defined as [2]â€Å"An electronic network providing access to millions of resources worldwide. University Libraries provide access to many periodical indexes through the Internet. Internet access is available on all floors of the Libraries.† Internet and the library both seems to be serving the same purpose but as the time goes by and world moves to new innovations and directions , the question arises is the latter going to replace the former . This essay compares and contrasts the Internet and an Library , how they share a common purpose and how they vary from each other while serving the purpose . Both the internet and an Library provides information on a wide array of topics but it may be not be necessary that library in United states has the books or journals about the History of Asian countries like china , India . Even if an American Library does has the books and information on the Asian history it may not as exhaustive as it would be in the libraries based in Asia itself . It is not possible to have the same set of books and information in all the libraries. Not all the books available in the Library of the Lindenwood university would be same as available in the libraries of Delhi University at India . Although noticeable works like the ones of Shakespeare would be definitely on the shelves of both the libraries .But its not always necessary that less known authors or journals will make to each library. While on the other hand information available on internet is universal , the same information can be accessed in all the computers worldwide . There is no regional version of internet just about anyone and everyone can access the same information whether it is done with a internet connection in India or in Americas .

Technology in Helping the Problem of Resource Scarcity

Technology in Helping the Problem of Resource Scarcity Nimra Hussain (11U0141) and Saeeda Malik Introduction A recurring theme in economics has been the economic growth fueled by an increasing consumption of finite resources that ultimately results in those very same resources unable to cope with its greater productive use. Resources here are any essential inputs to the economic process and are restricted to energy carriers, products of photosynthesis and other industrial raw material extracted from the natural environment. Such a practice is unsustainable and instigates the need for resource innovation so as to figure out how to generate growth with fewer resources. Much of economics runs around this one basic problem of resource scarcity and the aim of this paper is to emphasize on how human beings have created technologies or developed innovative methods to meet the challenges of limited resources available. More specifically this paper will review how technological innovation has made the problem of resource scarcity less onerous. The notion of scarcity as a constraint on economic growth goes all the way back to Malthus.(Malthus 1798, 1946).Only in recent decades has scarcity been seen as a driver of innovation and thus a driver of economic growth. There have been actual instances of resource scarcity and even exhaustion usually limited to a particular resource or country. However technological innovation in these instances have allowed for the resulting issues of scarcity to be rectified. For example natural fertilizer, guano and nitrate deposits from the West coast of South America were largely exhausted by the end of the 19th century. However superphosphate from bones and mineral apatites were a replacement for natural guano. Similarly, synthetic nitrogen-based fertilizers from coke-oven gas, calcium cyanamid and finally synthetic ammonia provided an alternative source of fixed nitrogen for agriculture (and military explosives). The search for alternatives to natural nitrates was deliberate and well-organiz ed. Germany led this scientific search, with the objective of breaking the British monopoly control over the Chilean sources of nitrates (Smil, 2001). Scarcities have not proven to be obstacles to economic growth. Far more often they have been stimulants to innovation that, in case after case, has led to new applications, new markets and accelerated growth rather than inhibiting it. An emerging scarcity is environmental assimilative capacity for wastes and pollutants. As it happens, most of the pollutants of concern, regionally and globally, are direct consequences of the use of fossil hydrocarbon fuels, especially coal. There is now a worldwide search for technological `fixes’ for the various environmental problems, from smog, acidification to global climate warming. But the most promising solutions involve reduced emissions, either by capture, treatment or storage of pollutants or by more efficient use of energy. Technical change is a dynamic process which includes the creation of new knowledge and technology, and the adoption of new technology by firms (Chavas et al, 1997). This technological change allows for increased production of outputs with the same amount of resources, or the use of fewer resources to produce the same amounts as before. In this way technological progress plays a vital role in the reduction of resource scarcity. It must be kept in mind that the improvements in technology do not augment the reserves of these resources, but rather augments the efficiency with which these resources are being used. A focal point in resource scarcity concerns the incentives for the discovery of reproducible technologies to substitute for finite natural resources that are being exhausted. According to Robson (1980) the date of innovation is random but can be brought forward through expenditures on research. However, according to Harris and Vickers (1995) the urgency to innovate increases as the stock of these already scarce resources dwindles. Looking at both statements intuitively it makes sense to think of technological innovation as being driven by the severity of its need as well as the expenditures needed to fuel its progress. Market responses to natural-resource scarcity automatically induce endogenous technological change that leads to resource conservation and substitution, and in turn, to the amelioration of scarcity (Barbier Homer-Dixon, 1999). Regardless of its source of provocation technological innovation plans cannot be set by countries in advance but will have to be done as they evolve with resource extraction. The idea of technical progress resolving the scarcity issue may seem simple but in reality the cost of acquiring any new knowledge and adapting it to local conditions, the adoption process of new technology may be slow. These lags between RD investment and its payoff can vary with each technology and each industry (Chavas et al, 1997) The most motivated to discover technologies are the importers of these scarce resources. Not only do they desire to overcome the problem of finite stocks but also according to Harris and Vickers (1995), to reduce their dependence upon resource producers, who often enjoy a considerable degree of monopoly power over them. The scarcer their stocks of natural resource the greater will be their RD efforts. It must also be kept in mind that innovation is exogenous and costly which explains why the possessors of large resource endowments are apprehensive towards its pursue*.Robson mentions that innovation and depletion should have opposing effects on growth as more efficient innovation leads to a slower rate of exploitation of the resource. Similarly, a larger output share for the depletable resource can lead to less innovation and a faster rate of exploitation. As mentioned earlier technological innovation is endogenous, and is determined by private and public sector decisions, rather than exogenously brought about into the economic system. If investment by these sectors is optimal then a constant growth rate of output and consumption can be maintained in the economy. Despite there being exponential population growth and scarce natural resources that are essential to production, technological innovations can allow for sustained growth and a long-run steady-state level of positive per capita consumption subject to certain conditions. These conditions as stated by Barbier and Homer-Dixon (1999) are that stable economic policies and social institutions should exist to facilitate endogenous innovations. There is a growing realization that solutions to ongoing and emerging threats to freshwater ecosystems and water resources require collaborative approaches that engage scientists, policy makers, the private sector, and other stakeholders (Chavas , 1997). Contributions by both sectors to technology have had a large and positive effect on productivity. For Chavas more specifically private RD has a strong short-term effect on productivity (after 5 to 10 years) and basically little longer term effect. In contrast, public RD has a small short-term impact on productivity, but a larger positive impact in the longer term (after 15to 22 years). Technology and research based knowledge trickles down or is transferred to and translated by policy makers and natural resource managers (Stelzer Kashian, 2014). models of knowledge transfer have been mentioned as participation, integration, learning, and negotiation. Such partnerships are essential to obtain sustainable outcomes. Once again looking at the link that overdependence on resource exploitation results in the economy remaining structurally tied to less innovative resource-based sectors, such as agriculture, minerals, oil, and other primary product sectors, and is unable to develop manufacturing and other value-added sectors that can produce learning-induced growth. In poor countries heavy resource dependent sectors have higher incidences of scarcity and conflicts over resource use. The severity of allocations can be enough to create social unrest and even violent conflict. In this way the little amount of stable institutional and policy environment needed to attract investments in innovation is disrupted coupled with the disruption of efficient and sustainable management that would have created the rents need to encourage long-term investment in innovation. Any resource crisis that does occur, its impact will be felt à ¯Ã‚ ¬Ã‚ rst and foremost by the poorest sectors of the population, for instance should a water crisis occur its impact would fall upon those that are dependent for their livelihoods on rain-fed or irrigated water in arid and semi-arid regions, where 52% of the world’s population lives (UNESCO-WWAP, 2006). Simply put poor countries such as our own will fail to achieve higher rates of growth because they fail to generate or use new technological ideas to reap greater economic opportunities. The possibility of technological innovation based solutions might not even be considered as increased scarcity often gives birth to competitive action by powerful elite groups and narrow social coalitions to defend their interests or to profit from the scarcity through rent-seeking behavior (Barbier Homer-Dixon, 1999). Robson on the other hand believes that if all the rent from the depletable resource is invested efficiently in innovation and capital, while no investment should occur, then consumption is constant. Truly technological innovation has played an important role. From Lopez-Gun and Llamas point of view thanks to virtual water, many water scarce countries have avoided a water crisis, particularly in politically unstable regions like North Africa and the Middle East. These revolutions of virtual water, groundwater and geographic information systems (GIS) are all created through scientific and technological innovation not in a vacuum but rather with the responsibility of states and other actors to carefully assess their full potential and limitations. Another instance is that of advances in technology, policy and management, such as improvements in pollution control measures (Dolan 1993) and fisheries regulations (Bruch 1999), that have benefited freshwater ecosystems. In China Hybrid corn is an example to demonstrate how innovation can help us overcome scarcity. Fish farming is another example. Intensive fish farming has increased China’s aquatic products supply by 10 times, fr eshwater aquatic products by 20 times over the last quarter of a century. This has greatly improved the food structure of Chinese people. Technological innovation is not without its flaws, as there is a cost of adjustment associated with such technologies such as those borne by workers that are displaced as a result (Stier, 1980). In conclusion innovation can indeed overcome resource scarcity as long as it is joined with government’s support for research, especially for those that of certain nature of public goods. There is also a requirement for qualified scientists and engineers, especially those who understand local needs. There needs to be team work by scientists and engineers coupled with an effective mechanism for knowledge diffusion so that invention and innovation can be used to increase productivity and create wealth. Recommendations Pakistan is another developing country where food in security and energy shortages are key indicators of resource scarcity and problems that are associated with it. In order to overcome this problem, technological innovations should be made use of which would help manage and consume these resources much more efficiently. Firstly, Pakistan should move towards more renewable sources of energy to reduce its dependence on other nations. Solar thermal energy is a cost effective resource in Pakistan (Mirza et al., 2003) and it’s consumption by the household sector can be encouraged by subsidizing solar panels. This would greatly reduce the demand for electricity from the government. The government should install small hydro power plants in areas where there is a natural flow of water to provide electricity to communities/villages that have no access to it or where it is not cost effect to install power lines. Secondly, the government needs to take large scale initiatives to not only develop but also promote the use of technology in large-scale sectors such as agriculture to ensure that producers are made aware of the scarcity of their product and also equip them with the information and ability to use technology to enhance their production capabilities and slow down the rampant process of scarcity, even if it is to a small extent. If such initiatives are streamlined by the government, it will go a long way in ensuring that resources are managed more efficiently and will also pave the way for a technological revolution in rural areas as people become accustomed to it. Thirdly, Allwood and Cullen (2012) argued that emphasis should be put on vehicles and buildings. According to them, vehicles consume a worryingly large amount of natural resources is gas and petroleum. Therefore, if manufacturers start producing lighter cars, that will significantly reduce energy use by almost 75 percent. The production of lighter cars entails not only the physical aspect but also other vehicular aspects such as a smaller engine and less horse power to ensure that the car burns less petrol. Toyota’s production and distribution of hybrid cars in Japan is a perfect example of such an initiative where hybrid cars can be seen just as frequently as normal cars, subsequently saving energy on a large scale. Furthermore, it is essential for governments all over the world to ensure that buildings are built using lesser amounts of steel and cement. Fourthly, industrial waste is a major contributor to scarcity of resources as a large amount of non-renewable resources is wasted during production. Allwood (2012) stated that one-quarter of steel produced goes to waste each year as it is not even used in the production of the final product. Ensuring that such high amounts of industrial waste are cut down will save already existing resources and make production more efficient and eco-friendly. Lastly, it is essential to improve water management and make sure that wat er is not wasted. This issue exists all over the world but is most apparent in countries like Pakistan where due to lack of water management systems, a lot of water is lost in transit and there are major issues of over-irrigation in some areas. This essentially means that some areas receive unnecessarily large amounts of water whereas some receive none at all. Ensuring a balances water management system will lead to better management of resources. This can be done by setting up a central regulatory framework that keeps a check on water distribution. Furthermore, this regulatory body should conduct research to evaluate which areas need what amount of water and subsequently make sure that the right amount reaches the right areas, in turn eliminating the concerns with water supply through proper management. References Harris, C. Vickers, J. (1995, Autumn). Innovation and Natural Resources: A Dynamic Game with Uncertainty. The RAND Journal of Economics, Vol. 26, No. 3, pp. 418-430. Lopez-Gunn, E. and Ramà ³n Llamas, M. (2008), Re-thinking water scarcity: Can science and technology solve the global water crisis?. Natural Resources Forum, 32: 228–238. UNESCO-WWAP. (2006). Water — a shared responsibility. UN World Water Development Report 2, New York: UN. Robson, A. J. (1980, February). Costly Innovation and Natural Resources. International Economic Review, Vol. 21, No. 1, pp. 17-30. Stier J. C. (1980, December). Technological Adaptation to Resource Scarcity in the U.S. Lumber Industry. Western Journal of Agricultural Economics Vol. 5, No. 2, pp. 165-175. Chavas, J. P. Aliber, M. Cox T. L.(1997, August). An Analysis of the Source and Nature of Technical Change: The Case of U.S. Agriculture. The Review of Economics and Statistics, Vol. 79, No. 3, pp. 482-492. Barbier, E. B. Homer-Dixon, T. F. (1999, March).Resource Scarcity and Innovation: Can Poor Countries Attain Endogenous Growth?.Ambio, Vol. 28, No. 2 pp. 144-147. Mirza, U.K. Maroto-Valer, M.M. Ahmad, N. (2003, December). Status and outlook of solar energy use in Pakistan. Renewable and Sustainable Energy Reviews, Volume 7, Issue 6, pp. 501-514. Stelzer, R. S. Kashian, D. R. (2014, June).The role of conservation partnerships between scientists and nonprofit agencies in freshwater science and management. Freshwater Science, Vol. 33, No. 2, pp. 670-673.

Genetic Regulation of Apoptosis and Organ Development

Genetic Regulation of Apoptosis and Organ Development This report reviews about the genetic regulation of apoptosis and organ development. The specific genes have been determined which cause these functions inside an organism proves to us some vital sequential systems concerning cell differentiation which in turn leads to the proliferation of the species. This report mainly gives you a clear cut explanation about how cell death and organ development act together in a progressive manner in concern with the development of an organism. The genes determined have been attested to be very useful in the field of treatment of diseases time and time again. And the review also dissertates on how the model nematode Caenorhabditis elegans has been used efficiently to determine the regulative genes of development and apoptosis. Which sequentially leads us to some predetermined definite advantages of the practical findings in the field of medicine. There are an enormous number of cells in the human body and in all organisms. Including an exception for numerous other bacteria and other microorganisms lower down the complication order. The basis of all these cells are two processes namely mitosis and meiosis. To be more specific in humans the fertilized egg is the source of all types of cells. From the fertilized egg in the humans to the innate process of mitosis and meiosis in the smallest of organisms all undergo cell differentiation. This process in defined as bringing in the characteristic of a specific cell to it specific function. These cells basically develop into various types of cells from their first stage of interphase in mitosis. But to remember that the zygotic stage never determines the specific function of the cell. Not only the newly formed cells undergo differentiation but the adult cells or the adult stem cells to be more specific undergo differentiation to form specific tissues and then organs and later to form a whole organism. The adult stem cells after their process of differentiation transfer their characteristics to their daughter cells in such a way that the daughter cells also exhibit the same characteristics as their parental generation. The cell differentiate along these lines that the whole morphology of the cell like the cell size, cell structure, membrane potential and even its response to signals alter. On the contrary cell death also plays a major part in cell differentiation and organ development. For example the process of metamorphosis in butterfly from larvae to the completely metamophosized butterfly or from the tadpole to a frog. The deaths of many cells are involved in this process, but very specific cells. Apoptosis is the word given for a programmed process of cell death without which the development of organs or any higher organism is most unlikely to happen. All the processes mentioned above are the consequences of gene manipulation within the cell. These are cont rolled by specific genes within a cell giving out certain signals as and when needed for different processes. Determining the genes that are involved in these processes is called as genetic regulation. Genetic regulation or gene evaluation plays a vital role in the field of medicine. This article discusses about the use of Caenorhabditis elegans, a transparent nematode worm as a specimen for determining the genetic regulation of organ development and programmed cell death or apoptosis. This specific species was short listed among many others as it had a very short time spanned cell cycle (Wood and William, 1988). Which consisted of only 959 adult cells in its generation cells making it very easy to analyse and determine the genetic regulation (Brenner, 1974). On the whole three scientists worked on determining the genetic regulation of apoptosis and organ development. Sir John Sulston was the first one among the three to initiate the experiment starting with developing all the techniques to study cell division in the nematode worm from its stage of a fertilized egg to a completely mature adult stage of the worm. (Sulston and Horvitz, 1977). Dr. H. Robert Howitz continued the work of Sir John Sulston by putting forward the question whether there was a genetic code for all death and development processes taking place in an organism. A specific genetic programmed that he suggested might be and determined the genetic regulations for the same processes in the worm (Jonathan and Robert, 1978). Dr.Sydney Brenner played his part by proving the work done by the previous scientists on determining the specific genes. He mutated those specific genes involved in the processes by using EMS or Ethyl Methane Sulphonate. This landed up on the result that, when these genes are mutated the organ development does not take place and consequentially lead to the death of the organism (Brenner, 1973) (Jonathan and Sydney Brenner, 1978). The work of all the three scientists helped in landing up in a theory and experimental proof of genetic regulation of apoptosis and organ development and also that there is a major connection between both the processes for the survival of the organism. The use of nematode worm was considered because it is difficult to determine the same in higher animals. The genes like Ced-3 and Ced-4 were primarily determined to be the genetic regulators of apoptosis and the proteins which codes for the initiation of these genes were used for degrading the DNA after apoptosis. Also making an understanding on how the dead cell is eliminated after the process of apoptosis. It was proposed that the same regulations also take place in higher organisms including humans as one of them with the help of homologous proteins like Apaf-1 in humans replacing CED-4 in C.elegans (Hua and William, 1997). The male and the hermaphrodite are differentiated by the morphology or by their internal organs. The male nematode is supposed to have 959 cells in its mature adult stage and makes it very easy to determine the genetic regulation. The picture above gives the lateral view of dissected C.elegans. The lateral dissected view clearly shows the simplicity of the organism and also on why the organism was narrowed down to study upon. (Sulston and Horvitz, 1977) This report mainly concentrates on the determination of genes involved in the process and how the two processes of development and death are linked in the complete life cycle of an organism. Determining the genetic regulation of the same plays a vital role in curing a hand full of dreadful diseases like Cancer, AIDS and Myocardial Infarction (Thompson, 1995). The unstoppable growth of cells inhibiting the process of apoptosis in the case of cancer (Morgan et al., 2006) and the death of cells inhibiting the process of development and initiating the process of apoptosis by activating all the available pathways (Explained in detailed in the proceeding pages) for the process of apoptosis in the case of AIDS (Perez et al., 2008). Determining the genes involved or genetic regulation has a major role in the treatment of these diseases. As genes and gene coding are the bases of every live organism in this universe. Genetic Regulation of Apoptosis and Organ Development: To just basically explain about genetic regulation before getting deep into the degree of the paper, genetic regulation is the process of turning on or turning of the genes that are needed and those of which are not needed respectively. The first ever gene regulation developments were on the lac and the trp operon model. Basically it is a system used for saving up the enzymes and using them whenever necessary and not wasting them by accumulating them by continuously producing them on the contrary. These are helped by the genes. And for better understanding s schematic is given below of the overall process of genetic regulation. Introduction to Apoptosis Apoptosis is derived from the Greek language meaning dropping off or falling off of parts. This I suppose does not give the appropriate meaning but the term was coined according to the preliminary discoveries of researchers regarding the same. The term was titled to fit the process as there were findings and literature that stated the dropping of all organelles (not literally) of the cell after the depletion of the cell wall in the continuum of processes of apoptosis. The term generally means programmed cell death, which is defined as the well timed suicide of the cells by gene regulation as and when needed by the organism. This is the exact process that takes place in all organisms from a single celled to a multicellular complex organism. Apoptosis regulates certain morphological features of the cell leading to its death in the coming cycles of apoptosis. The morphological changes include bleebing, loss of cell membrane, asymmetry of the cell, fragmentation of the DNA and many other structural and functional changes (Alberts et al., 2008). Atrophy is caused in the final stages of apoptosis which can lead to the complete destruction of the cells. The process was primarily considered to be incomplete as it was not known how the cells were dissolved after their death as the organelles after the cell death would cause to create an unwanted mass in the organism. But latter it was determined that the cells after the process of apoptosis ended up in creating apoptotic bodies which were engulfed by other cells using pseudo arms and then were dissolved using the proteins that code for the gene to regulate the process of apoptosis (Walker and Sikorska 1994). During the years of the primary experimentation this process was written along with the process of necrosis which was the premature death of cells due to external effects like toxins, hazardous chemicals or radiations. But further experimentation and trials proved that apoptosis was a self-inducing factor of cells for their suicide in order that the following processes of or gan development takes place without obstructions. When human trials are concerned it is to be noted that about 50 to 70 billion cells die each day in the same process, where at the same time daughter cells are generated. Cell death plays an important role in organ development and tissue homeostasis. The regulation of cell proliferation by Programmed Cell Death (Apoptosis) contributes to organ and tissue development and differentiation to a great extent. Depending upon the time and clinical impacts many genes change their expression during organ development. The success of organ development completely depends upon the interaction between the maintenance of cell survival and cell death. Cell death plays a significant role in promoting growth and tissue development of an organism. Generally when cell death occurs, the following points are to be taken into account, Development of normal tissues and cell death. Regulation of cell cycle and expression of genes. Determining the cell death pathway. The pathway acts as a molecular target for therapy (Prof. Dr. M. Nurhalim Shahib, 2001). When cells die, the contents of the cell are released in the surrounding and it causes inflammation or swelling which is termed as necrosis. When cells die during normal development or tissue homeostasis, they tend to condense and shrink and the dead cells are phagocytised by neighbouring cells before the contents of the cell get leaked in the surrounding. They do not induce any inflammatory response unlike the necrosis. This process is termed as Apoptosis or Programmed Cell Death (Kerr et al., 1972). Apoptotic Pathways Extracellular and intracellular pathways are the two terms that are concerned when there is a death of a cell taking place or a death of group of cells. Extracellular pathways are the subjecting of cells to toxin or hormones or growth factors which can in turn lead to the death of the cell. This not of much concern in our review as we are concentrating on the pathways of apoptosis. To get a brief knowledge about the death of the cells we should know that the death of the cells can take place by sensoring the signals from inside the cell or from the outside of the cell. Apoptosis mainly takes place by transducing signals from the inside of the cell. This process can be put into two main categories namely positive induction and negative induction. Induction means the inhibition of the reaction and hence positive induction refers to the undergoing apoptosis reaction. To give a brief about the extracellular and intracellular processes. The intracellular processes will be explained in detail below and the extracellular process is simply the transducing of signals in case of unstable environment or the sequential crossing of the plasma membrane. Intracellular signalling has many different pathways which follow a definite sequence of steps. These including some like the binding of receptors by glucorticoids in the presence of high calcium concentration. All processes in the cells are initiated by enzymes specific enzymes that code for specific genes to be activated for the following reaction to take place. Hence in the contrary these proteins or enzymes can also be used to inhibit the reaction by finding out the genes which code for the enzyme to be produced. The process of apoptosis is mainly targeted to the mitochondria of the cell which then ceases almost all the functions the cell. For explaining in detail the intracellular processes that are taking place we need some specific pathways for a deep understanding. Many pathways are proposed and on literature which we are going to discuss in brief in the following pages of my report. Mitochondrial Regulation of Apoptosis Briefly explaining about mitochondria, they are the power house of the cell and supplies energy for the complete survival of the cell without which the cell is not in existence. Obviously needless to say that without the functionality of the mitochondria the cell is just another non living organism without any appropriate use. This vivid function of the bacteria is used by the apoptotic pathways. There are two pathways by which the cells are forced to death by inhibiting the function of the mitochondria. They are the intrinsic and extrinsic pathway. They both vary in the pathways but the end product is always the death of the cell. (Susin et al., 1999). The intrinsic pathway is basically the swelling up of the mitochondria by the formation of pores. This is formed by the binding of Cytochrome C to the apoptotic protease activating factor and then followed by the process of apoptosis. On the other hand the extrinsic pathway is the decrease of the membrane potential of the mitochondrial membrane by the action of nitric oxide and also the increase of the permeability causing a leak of enzymes inside the mitochondria. This causes the uncontrollable swelling of the cell and also causes blebbing. When the cells continue to swell it leads to the damage of the cellular membrane that eventually leads to cell death. These are reported to be caused by the SMACs which are stated to be secondary mitochondria derived activation of caspases. This can be proved to be the right opposite to the intrinsic pathway as this process deactivates the pathway that inhibits apoptosis by binding to the inhibition of apoptosis proteins or namely IAP rather than the intrinsic pathway that directly induces apoptosis. (Mayer and Oberbauer, 2003). When we get to compare both the processes we tend to end up in a result which states that the damage of the cell is indistinguishable between the two. 2.2.2 Caspase Independent Pathway Caspase in considered as the most important protein in the proper functioning of the apoptosis cycle. But it is proved that the apoptosis can also take place without the activity of the caspase protein. This takes place by a binding factor known as Apoptosis Inducing Factor (Cande et al., 2002) which only needs transduced signals rather than the caspase binding (Magali et al., 1999) 2.2.3 Signal Transduction Signal transduction is generally described as the process of transferring signals. The same as mentioned above this also involves both extracellular and intracellular signals. This process is also called as the shape shifting process as the morphology of the cell is completely changed after this process takes place. There are two different pathways TNF and Fas pathways namely. Figure 4: TNF and FAS Pathway within the cell. The diagram gives an easier explanation for the Fas pathway including the caspase binding reaction. It also shows many other proteins involved in programmed cell death. The TNF and the Fas pathways are two completely different pathways with the same functionality as to programmed cell death. They assist mainly in transferring signals not only from the inside the cells to the point of pathway commencement but also from the exterior of the cell to the important signal transducers inside the cell. (Philip, 2004). The TNF pathway or the Tumor Necrosis Factor pathway. The pathway is commenced by the binding of TNF R1 and TNF R2 which in turn leads to the initiation of caspase activating pathway which then eventually leads to the death of the cell. Both the pathways to be mentioned are results of binding. This pathway was also proved to be leading to one too many activations of transcription factors, the cause of numerous diseases (Chen and Goeddel, 2002). The Fas pathway also follows the same binding pathway as the TNF pathway. Only that the activation of transcription factors is unlikely to happen and the binding here takes place in caspase 8 and caspase 10. Binding of Fas and Fas L takes place along with the Death Inducing Signaling Factors or DISCs (Wajant H, 2002). 2.3 Extracellular Control of Apoptosis Programmed cell death or apoptosis have found to be activated or suppressed by extracellular signals from other cells apart from the apoptotic cells by controlling the mechanism. These extracellular signals are sent majorly to prevent programmed cell death. (Raff, 1992). There are a few examples to demonstrate how the signals activate or suppress apoptosis. Most of the vertebral cells tend to undergo apoptosis when cultured at a low density with the secretion of extracellular signals on their own. For Example- Blastomeres have the ability to survive and divide even in the absence of extracellular signals. The cells from tissues that are made of only single cell types have the ability to produce self-survival signals (Biggers et al., 1971). In some cells, a combination of several signals from different cells is required for their survival in a long term aspect. Example- The vertebral neurons during development compete for signals for their survival which are secreted by the target cells that they innervate. In this process only half of the neurons get enough signals to survive and the rest undergoes programmed cell death. Therefore, the normal death can be prevented by injecting exogenous Nerve Growth Factors (NGF) to the neurons. Similarly when the genes that code for NGFs are inactivated or by addition of anti-NGF antibodies, all the neurons undergo Apoptosis. Usually both inactivation and injection of NGFs are carried in a neuron to provide a balance between the number of neurons innervating the target cell and the unwanted neurons that target inappropriate cells (Levi, 1987). Some cells are triggered by programmed cell death inducing signals which suppresses the action of the signals that are responsible for the survival of the cell. Example- In amphibians like tadpoles, a systematic induction occurs at the metamorphosis stage where the cells in the tail undergo apoptosis due to the increase of thyroid hormone in the blood and this facilitates the resorption of the tail (Kerr et al., 1974). 2.4 Overall Process of Apoptosis- Morphological Concern The figure above gives us an easier understanding of the morphology of the cells in the course of Apoptosis. The diagram gives us a clear cut explanation about how normal cells receive signals and then followed by cell shrinkage and nuclear collapse leading to death and formation of apoptotic bodies to the complete lysis of the cell. (Philip, 2004). Observation Causes Cell shrinkage and rounding Breakdown of proteinaceous cytoskeleton by caspase. Density of Cytoplasm Signal transduction by TNF pathway or Mitochondrial regulation Tight packing of organelles Signal transduction by TNF pathway or Mitochondrial regulation Chromatin shrinkage against nuclear envelope- Phykonosis Condensation of Nucleus Karyorrhexis Degradation of DNA Breaking of Nucleus Blebbing (Mathew et al). Localized decoupling of the cytoskeleton from plasma membrane Phagocytosis or engulfing of dead cells Usually present on the cytosolic surface but spread by scramblase Table 1: Tabulated format of the observations during Apoptosis of the cell and their primary causes. 2.5 Role of Inhibitory or Promoter genes in Apoptosis The cells after undergoing apoptosis in all tissues and animals appear similar and this cell death gets involved in many operations that are active and intracellular which can be promoted or inhibited by physiological or pathological stimuli. Regulation in Caenorhabditis elegans The genes responsible for apoptosis was first identified in a nematode, Caenorhabditis elegans, related to cell death and its control (Horvitz et al., 1982; Ellis and Horvitz, 1986). Initial genetic studies in C.elegans led to the identification of a gene called Ced-3, a promoter gene responsible for programmed cell death to occur during the development of the worm (Ellis et al., 1991). The Ced-3 gene codes for an enzyme which is Cysteine Protease (Yuan et al., 1993). The gene cleaves the substrate after every active and specific aspartic acid sites and they get activated by cleaving at the aspartic acid sites. These are now referred to as Caspases (Alnemriet et al.,1996) The caspases mediate the apoptosis by cleaving at specific intracellular proteins that are of high selectivity and these proteins in turn activate the apoptosis process (Chinnaiyan and Dixit, 1996). Similarly there are many genes that inhibit the apoptosis process in the nematode, Caenorhabditis elegans. One such gene is Ced-9, which belongs to the same family as the Ced-3 and this gene inhibits apoptosis in the nematode (Hengartner and Horvitz, 1994). If Ced-9 is activated by disruption or any mutation, the worm dies at a very early stage when compared to the usual growth. Therefore Ced-9 is necessary to prevent programmed cell death if the cell has to survive in the developing worm. (Hengartner et al., 1992) Regulation in Mammalian cells Similar to the nematode there are many genes that act as inhibitors or promoters of programmed cell death or apoptosis in mammalian cells also. They in turn contribute to organ and tissue development. Certain genes like Bcl- 2 and Bcl- XL act as inhibitors that inhibit programmed cell death. Genes like Bax and Bak act as promoter genes. They promote programmed cell or apoptosis. The average ratio of the inhibitors to the promoters determines the capacity of a mammalian cell to undergo apoptosis (Korsmeyer, 1995). Bcl- XL, in three dimensional structures is noted to function as a pore forming protein in the intercellular membrane where the genes are actually present. (Muchmore et al, 1996) When the Bcl- 2 and Bcl- XL is disrupted in a mammal like mice, the animal tends to die either as an embryo itself of in the post natal stage due to excessive programmed cell deaths in particular organs. When Bax is disrupted, normal programmed cell death or apoptosis process itself fails to occur (Deckwerth et al, 1996). Although proteins are required for the apoptosis process, inhibitors of RNA or protein synthesis often inhibit apoptosis indicating that transcription and translation are required to activate the programmed cell death process. 2.6 Importance of Programmed Cell Death (Apoptosis) In the mutant nematodes, where the apoptosis process is deficient, it is found to have a normal life span. But whereas apoptosis process deficient flies are found to die at an early stage. The vertebrates exhibit results similar to that of the flies. This difference is due to the inhibitory and the promoter genes in the different organisms and their relation to organ development and tissue homeostasis. 2.7 Consequences of Defective Pathways The consequences caused (diseases) are only caused by the defective apoptotic pathways. Where normal apoptosis does not take place. The only way by which the flow of apoptosis is disrupted is by deferring the signal. When the pathway is inhibited the growth of the cell continues and the cells live more that they are supposed to actually live and differentiation of these cells also transfer the fault to their progeny. Which most probably leads to cancer. The inhibitor or the suppressor as we call it here binds to caspase preferably 8, 9 or 10 here in this case and stops the cell death. AIDS: This specific viral protein deactivates the anti-apoptotic Bcl-2 and triggers the mitochondrial regulation pathway to progress the reaction at a higher pace. FAS mediated apoptosis is increased and the death rate also increases (Perez et al., 2008). Cancer: This disease is a causative of inhibition of apoptosis. Where the X-linked inhibitor of apoptosis protein plays a vital role. When the cells do not die at the specified time a tumor is produced leading to cancer (Ott et al., 2006; John and Kerr, 2006). Having mentioned about the disadvantages of the defective apoptotic pathways, the advantages of apoptosis is none other than the development of organs by programmed suicide of the cells As I have mentioned before, there are uncountable processes that are taking place inside an organism every milli second. The process of apoptosis has its own significance amidst all the other. It can also be rightly named the mother of all processes as apoptosis is the cause of organ development and also the root cause of development of any organism. 3. Organ Development Organ development is also known as organogenesis. For our clear understanding we can explain it as the budding of organs from the growth cycle beginning from the form of a zygote. This routine is followed in all organisms which is just the consequence of death of cells in a programmable manner. The cells from the stage of division are never pre-determined the cells later are differentiated to form certain organs or organ systems. This programmed process of cell death coupled with organ development is the most important course of action in any organism as it determines the growth or death of the same. Then which can be followed by all the regular functions of the gene. To give a brief description about how organ development takes place, it is the proceedings of the ectoderm, endoderm and mesoderm to develop organs and organ systems. The embryo is at its weakest in this stage of development which may lead to anomalies or discretion. The soul reason behind this process on paper to progress in a timely manner is the proper differentiation of cells by gene coding. Which can literally imprint an impact on the cells to develop only to certain organs by coding them. Stem cells play the most vital part. Being the cells that can undergo easy differentiation combined with a superiorly faster rate of proliferation when compared to normally proliferating cells. Figure 9: Development of Endoderm, Mesoderm and Ectoderm into specified organs by genetic coding. The layers are distinctively separated and differentiated into specific organs and organ systems by genetic regulation. This differentiation is defined by the genes that regulate the development. Endoderm à ¯Ã†â€™Ã‚   Forms the tissue within the lungs and pancreas (Anne and Douglas, 2000). Mesoderm à ¯Ã†â€™Ã‚   Function of forming muscles and also the tissues of kidneys. Ectoderm à ¯Ã†â€™Ã‚   Primordial function of formation of tissues with the epidermis and most important characteristic of formation of neurons. 3.1 Causes of improper organ development There are many conditions that can cause improper organ development. Some of them like Toxicity, high amounts of radiation in the form of zygote or even in the higher order in the development line can cause permanent shift from the frame of reference. Other prime movers for this plight are some like tobacco and alcohol and other brain stimulating drugs. These obstructions of organ development due to mutation can been experiment on Arabidopsis thaliana and proved to cause the same effect on humans (Stein et al., 2004). This is because human field trials on this has been stated illegal all around the globe. Irregular apoptotic pathways can also be mentioned as some the reasons for the cause of improper organ development. But the root cause of everythig always lies in its beginning that is the primary infection of exposure to hazrdous materials or drugs. This can interfere in the primary pathway, leading inturn to the defective pathway of apoptosis. The defective pathways in apoptosis c an be the major cause of the irregular or improper organ development. May be considered as one of the most important reason for improper organ development. One of the most important reasons for improper organ developent is the cause of genetic mutations. The genetic mutations are caused by the radiotions or hazardous toxins that I have mentioned before. But what leads to improper organ development is genetic modification or mutations in the gene. This can lead to permanent damage of the cell or the gene. This gene damaged, specifies to an organ. Finally the organ is completely damaged due to the mutation of the gene that tends to regulate that specific organ of the organism. Also considering the fact that the cells can also die due to mutations causing permanent damage in the organ development phase of the organism. 4 Applications 4.1 Clinical applications Many diseases like cancer, auto immune diseases, neuro-degenerative diseases do not either inhibit apoptosis or leads to inappropriate activation of apoptosis. They do not completely eliminate harmful cells which lead to loss of all the essential cells that prevent the oncoming of these diseases. Therefore, potential therapeutic strategies must be incorporated by including small molecules that either inhibit or activate certain target proteins that are responsible for apoptosis (Murphy et al., 2003).Generally there occurs a natural delay in the activation of Caspases after any injury and this delay allows enough time for treating the molecules that target Caspases. They are said to show therapeutic applications in preclinical studies (Reed, 2000; Nicholson, 2000). Bcl-2, another inhibitor gene of apoptosis, plays a vital role in the mitochondrial pathway and is regulated in many cancer cells. Introduction of an antisense Bcl-2 oligo molecule has shown promising results in preclinical trials in SCID mice and phase III clinical trials (Reed, 2000; Nicholson, 2000). There is something called, Inhibitors of Apoptosis (IAPs) that are of potential therapeutic targets for treatment of diseases. Some cancers over expresses the IAPs that is associated with the genes responsible for the resistance of apoptosis. One such gene is called Survivin (an IAP) which is involved in cancer cells. By eliminating this Survivin, the cancer cells become more sensitive to drugs that initiate apoptosis (Nicholson, 2000). 4.2 Immunoblotting techniques Cytochrome C, an indicator of apoptosis is attached to the apoptotic cells along with the presence of genes responsible for apoptosis and immunoprecipitates were formed. By addition of anti-Cytochrome C or anti-Bc

Autism in Children :: detection, intervention, education

All children deserve to have an equal chance to learn and perform in any number of categories. The only problem is that not every child can function correctly for various reasons. The condition that I am covering is autism. Autism is a difficult symptom to correct because it is a brain disorder that takes time and much work with doctors and teachers. I wanted to learn more on this disorder because I have a family member that have this condition. Autism affects communication skills, social skills, creativity skills, and learning skills. The ways to help correct these symptoms would be early detection, early intervention, and how to educate children with autism. Every parent wants to know what causes autism for their child. The only problem is that no one knows what causes autism. There are many signs and different theories, but no answers to what causes autism. Many different methods have been conducted to see the cause of autism. Methods like brain research, genetics, and neurochemistry have not solved this dilemma. The causes of autism have not been solved, and might never be discovered. Parents want to know if their child can be cured and be able to live a normal life. The answer to that is no and yes. There is no cure for autism, but with the proper treatment and education, a child can grow and live a very normal life. There are many cases of people with autism living a normal based life, even though they still have autism. Autism is a life long condition that can not be cured, but people can still live normal lives. One person in particular (Peter) interested me as he lives a very normal life and is an inspiration to not only autistic people, but to everyone, Today, things are much easier for me. I go to Inver Hills Community College, where I?m working for my associate of arts degree. I am very hopeful about my future. I?ve taken some very difficult classes in geography, but I have passed all of them with a fairly decent grade?This past October, I gave a talk in front of nearly three hundred people up in the Twin Cities about my autism?I talked about what autism felt like for me, and I told some funny stories?On the whole, this talk was a very big success for me. My talk brought tears to the eyes of many.

Puritan History :: essays research papers

in the 17th century some Puritan groups separated from the Church of England. Among these were the Pilgrims, who in 1620 founded Plymouth Colony. Ten years later, under the auspices of the Massachusetts Bay Company, the first major Puritan migration to New England took place. The Puritans brought strong religious impulses to bear in all colonies north of Virginia, but New England was their stronghold, and the Congregationalist churches established there were able to perpetuate their viewpoint about a Christian society for more than 200 years. Richard Mather and John Cotton provided clerical leadership in the dominant Puritan colony planted on Massachusetts Bay. Thomas Hooker was an example of those who settled new areas farther west according to traditional Puritan standards. Even though he broke with the authorities of the Massachusetts colony over questions of religious freedom, Roger Williams was also a true Puritan in his zeal for personal godliness and doctrinal correctness. Most of these men held ideas in the mainstream of Calvinistic thought. In addition to believing in the absolute sovereignty of God, the total depravity of man, and the complete dependence of human beings on divine grace for salvation, they stressed the importance of personal religious experience. These Puritans insisted that they, as God's elect, had the duty to direct national affairs according to God's will as revealed in the Bible. This union of church and state to form a holy commonwealth gave Puritanism direct and exclusive control over most colonial activity until commercial and political changes forced them to relinquish it at the end of the 17th century. Because of its diffuse nature, when Puritanism began to decline in America is difficult to say. Some would hold that it lost its influence in New England by the early 18th century, but Jonathan Edwards and his able disciple Samuel Hopkins revived Puritan thought and kept it alive until 1800. Others would point to the gradual decline in power of Congregationalism, but Presbyterians under the leadership of Jonathan Dickinson and Baptists led by the example of Isaac Backus (1724 - 1806) revitalized Puritan ideals in several denominational forms through the 18th century.

The Character of Norma Jean in Shilo Essay -- Shilo Essays

The Character of Norma Jean in Shilo      Ã‚  Ã‚   Norma Jean Moffit is a major character in Bobbie Ann Mason's "Shilo" who undergoes a profound, yet subtle change. She had to marry at the age of eighteen to the man who got her pregnant, and in a cruel twist of fate, the child dies suddenly of crib death. Now at the age of 34, she is ready to have the life she feels she always should have had, however she is stuck in a loveless marriage to a man whose interests are the opposite of hers. Her decision to leave her husband, Leroy, at the end of the story seemed a long time in coming, and various aspects of her character revealed that desire. These aspects of her character were her devotion to self-improvement, her inability to communicate with her husband, and her apparent unhappiness that Leroy has returned home for good.    From the very beginning of the story, Norma Jean is portrayed as a woman continuously trying to better herself. She takes the opportunity of Leroy's rehabilitation from his accident to start bodybuilding. After the body building class is over, she takes a comp...

Poverty in Canada or USA

During the period between 1929 and 1953, the United States occupational pay ratios and earning inequality is declined, mainly across World War II (Ober 1948, Phelps Brown 1977, Williamson and Lindert 1980, Goldin and Margo 1922b). The evidence showed that the condition of income inequality was occurrence in that period. Moreover, the problem of income inequality is declined. But, the problem of income inequality is existed. The government cannot spread the income distibution evenly. Many reasons obstructed the income distribution evenly. In my discussion, I concentrate to explain five reasons to influence the income distribution in the United States in the 20th century. Changing in social norms is related to the income distributions. Many people think that women represented a cheaper alternative for employers. Their jobs were viewed as temporary to be abandoned in favor of marriage and a home. High turnover combined with a large pool of replacements in any occupation will tend to depress wages, but it also means there is no incentive to provide career opportunities or invest much effort to train persons for more responsibility. Consequently, women tended to fill the more specialized and lower-paying work, while men moved into the new office manager roles. The fact is that clerical, service, and sales work does not yield significant financial returns to people with more formal education or longer work experience (Bibb & Form, 1977). In large part, this is because most of these are low ceiling careers, lacking in meaningful promotion opportunities for higher paying positions. The jobs have been filled advantageous position by one sex or the other. The point is strongly influencing the income distributions. The point of the unionization is related to the income distributions. Unions have improved wages and benefits, increased job security, and protected workers from discriminatory managerial decisions. Male workers are more likely to be members of trade unions, thus enjoying the advantages of collective bargaining for wages and earning more than women (Flaherty & Caniglia, 1992). Overall, women are about half as likely to be union members as men. Rinehart wrote, ? Â § This accommodation to capitalist power was formalized in what is known as the post ? V World War II compromise forged in the midst of the intense class struggles of the 1940s. This settlement between labor, big capital, and the state featured the establishment of a new industrial relations system and stipulated a set of trade ? V off. Unions were legally recognized and accorded organizational security.? (P. 184) Changing in the education level of the population is related to the income distribution. In the U. S, the financial return to a university or college degree also declined during the 1970s. One explanation of this phenomenon was the substantial increase the proportion of the population going to university, particularly the entry into the labor force of the ? Baby-Boom? generation during the 1970s (Welch 1979). Freeman (1976, 1980) argued that the demand for educated workers also declined, so that not all of the change in relative earnings could be attributed to temporary developments on the supply side. Dooley (1986) concluded that the entry of the large baby? Vboom cohort during this period did lower earnings growth for this group, but that this demographic effect could not account for the observed harrowing of earnings differentials by level of education. Dooley? s results thus suggest that demand ? V side forces may also have played a role. Changing in the age structure of the population is related to the income distribution. The shapes of the earning streams reflect the main key factors which is earnings increase with age but at a decreasing rate. This concave shape reflects the fact that individuals generally continue to make human capital investments in the form of on-the-job training and work experience once they have entered the labor force. This job experience adds more to their productivity and earning s early in their careers due to diminishing returns to experience. However, to the extent that education increases productivity, individuals with the same amount of work experience but more education will earn more, perhaps substantially more. Migration is related to the income distribution. Economic theory predicts that the forces of competition would serve to reduce pure regional wage differentials so that they reflect compensating differences, short-run adjustments, or noncompetitive factors. Those forces of competition were the movement of capital from high- to low-wage areas, and the movement of labor from low- to high-wage areas. Empirical evidence tends to verify the implications of migration as a human capital decision. In a recent study, Osberg, Gordon, and Lin (1994) explore the determinants of interregional and interindustry mobility of individuals in the Maritimes. Using the 1986-87 LMAS, they find that younger individuals and those with higher expected wage gains are more likely to migrate. As well, the process of migration tends to reduce the regional disparities that induce the migration decision. In conclusion, the five reasons are influence the income distribution in the United States in the 20th century. The social norms show that the income inequality is happened between men and women. The unionization shows that the unions have a power to improve the wages and benefits for their members. In this situation, the income inequality is happened between union? s members and non-unions members. Although the demand for education workers was declined, education people still earn more than the uneducated people do because they have an expertise knowledge and experience. Migration is benefits for the young individuals. They can have a chance to prove themselves. Therefore, the movement of migration decreases the regional disparities.

Biology Pearson Textbook Homework Questions Essay

a.There are several differences between RNA and DNA is that are key. DNA has deoxyribose sugar while RNA has ribose sugar. Secondly b.RNA is generally single stranded and not double stranded. Lastly RNA contains uracil in place of thymine. c.The three types of RNA are messenger RNA, transfer RNA, and ribosomal RNA. Messenger RNA is the â€Å"mirror image† of the DNA that encodes the amino acid sequence for the protein specified by the gene. The Transfer RNA transfers the amino acids to the ribosomes from coded messages. Ribosomal RNA helps build the proteins on the ribosome. d.The reason that so many RNA molecules are produced more than DNA molecules because you only have two copies of DNA in one cell. If only two proteins could be produced at a time it would take the cell a much longer time to do the functions that it needs to perform. 2. a.During transcription segments of DNA serve as templates to produce complementary RNA molecules. b.I think that the mRNA would not code properly for the correct protein so none of the functions could occur properly. No proteins could be made without the mRNA. 3.RNA George a.I am unspecialized and am very willing and capable to do any job. I can be used in the messenger, transfer, and building proteins areas of work. As a messenger I can encode the protein sequence that is given to me from the genes. As a â€Å"transferist† I can transfer the amino acids to the ribosomes. Finally as an rRNA I can assemble proteins. Please consider my application.

A Uniformed Education Essay

Even though it is believed that students need to make life decisions based on their own standards, instead of the procedures and guidelines set for them, and that this is vitally critical for them as they grow into adults. Uniforms are a good idea as it causes students to focus on their academics and learning rather than on latest fashions or what the next student is wearing, also to respect themselves, their instructors and each other. Students are more likely to feel safe in schools with uniforms and they are also more inclined to attend classes and perform better academically. Faculty members in an inquiry believed that uniforms increased the learning climate by reassuring morality amongst students, augmenting the communication between teachers and students and bettering the administration of discipline. Many school officials agree that wearing uniforms helps decrease bullying and student detachment, and many educators are convinced that school uniforms increase students’ a bility to thrive in the classroom. As Huss (2007) states, â€Å"School uniforms are tangible; they are seen as a concrete and visible means of restoring order to the classrooms.† Uniforms cause change in appearance and performance while in class. First, students are more likely to feel safe in schools with uniforms and they are also more inclined to attend classes and perform better academically. Students perform better academically when they feel safe and are not threatened in school. There has been a lot of scrutiny concerning school safety, due to the increased activity and violence of gangs in schools. After taking note of these actions (increased violence and gang presence) officials are always considering ways to establish the security of the students and the faculty. King (1998) states, â€Å"Those who fear for their safety in school or on the way to school may not learn effectively, and they may turn to truancy as a viable alternative to facing daily threats of violence.† School safety, a  more disciplined student and student learning is believed to be the outcome if school uniforms would be enforced. Wearing school uniforms helps a school limit the wearing of gang colors, theft and school violence. Enforcing school uniforms should be taken seriously considering the ability of them making a student feel secure and safe to learn. When uniforms are required and worn it makes it easy to identify those that are not from the school or that are actually out of uniform by wearing regular street clothes. Students from schools where uniforms were required reported they did feel more safe and compelled to be concerned more about their education and succeeding in the classroom than to have to identify who was a member or which gang from day to day. King (1998) states, â€Å"Approximately one in four students reports worrying about becoming a victim of crimes or threats at school, and one in eight reports having been victimized at school.† The wearing of school uniforms should be expected in all schools and not just targeted areas; this would increase the true benefit of wearing unifor ms in our education system. Creating a system where uniforms are worn in all schools would limit the thought of a school that actually has a uniform policy in place as being considered a bad school or unsafe to send a child. Uniforms should not be associated with a schools safety and or truancy problems. The safety of our children should be a priority every day. Additionally, teachers in a study believed uniforms enriched the schooling climate by stimulating morality amidst students, augmenting the interactions between the teachers and students and bettering control. Similarly, of the 5,500 principals surveyed as attendees of the National Association of Secondary School Principals’ annual conference in February 1996, more than 7-% believed that requiring students to wear uniforms to school would reduce violent incidents and discipline problems. Moreover, greater than 80% of Long Beach Telegram readers supported uniforms. (King 1998) â€Å"A school reported the effects of wearing uniforms and in the first year alone crime decreased by 36%, sex offenses by74% and physical fights among students by 51%.† (King 1998) Students have shown to behave at a higher standard when in uniform and it also has been reported to have an effect on the interaction between a teacher and student. When in uniform students mannerisms are different and they carry themselves in a higher regard. It is believed that both the students and teachers operate based on the way they are dressed. A school  official has been quoted as saying â€Å"Students here understand why they are in school†; â€Å"Students work hard to complete their assignments†; and â€Å"Students in this school have fun but also work hard on their studies.† (Murray, R. K. 1997) This in no way means that all students will act accordingly and excel academically, but it would assist in creating an environment where both students and teachers were a ppreciative of their school and more considerate to each other. It is believed that teachers interact differently with students when they are clothed in a more uniformed manner. Students have also been noted as having better mannerism and more care in how they handle each other as well as the faculty. Finally, the most important reason uniforms are a good idea as it causes students to focus on their academics rather than on the latest fashions because â€Å"wearing uniforms helps students to get into â€Å"learning mode† and reminds them to respect themselves, their instructors and each other.† (Wade, K. & Stafford, M. 2003) The administrators instantly point out that normally; purchasing school uniforms for a school year can cost between $80 and $90 per child, this cost is lower than what parents would spend when having to buy the designer clothing that a student desires. So, a student and parent would be better off purchasing uniforms financially which is looked at as a bonus in these economic times. Students in a school that requires uniforms are less likely to feel or receive peer pressure because of their lack of the designer clothing that other families may be able to afford. In a climate where uniforms are mandatory your family’s financial situation is not noticeable thus making it a more comfortable learning environment. A parent was quoted saying, â€Å"I know I spent less money and needed far fewer items of clothing for my children when they wore school uniforms.† (Walmsley, A. 2011) This also lessen the occurrence of the morning fights between parents and students as to what to wear for the day the selection is simple and minimal at the same time. At this age youths are at the point of attempt to find their own individuality and ideas of what suits them clothes wise be it baggy or tight jeans, cartooned t-shirts, and political clothing. Getting away from wearing those types of clothing and requiring a uniform causes the student to not focus on what someone is wearing but instead their schooling and academics which is way more important. Fashion should take a backseat when it comes to your education. A youth’s individuality can be expressed in other ways if shown  and at the same time there should be limits set on the possibilities of accessories worn with the uniforms. Students have been intensely wounded and or killed for their designer shoes, clothing and accessories. School uniforms are believed to cut down on these occurrences. Being dressed in a different manner has been shown to cause a different reaction in class and in a student’s day to day life. School climate has been shown to be related to student achievement as well as how students behave and feel about themselves, their school, and other individuals. Furthermore, positive school climate has been identified as a characteristic of an effective school. Given the significant impact of school climate on student achievement, practitioners should consider these new findings when considering implementing a school uniform policy as a means of improving school climate and student behavior. (Murray, R. K. 1997) Requiring uniforms in schools changes the climate and the reaction to learning significantly. Walmsley (2011) states, â€Å"Because students dress in uniforms, they’re reminded that their â€Å"job† is to be a student.† A uniform causes a different behavior and creates such a reaction in the students that their attitudes ch ange automatically. On some occasions students have even decided to opt out of the days allowed for â€Å"street clothes† after they have experienced a school uniform environment. When dressed in street clothes students tend to behave in a manner of â€Å"play† and not take their education as serious. Just as stated before when in uniform â€Å"they’re reminded that their job is to be a student,† it’s presenting them with the idea that during these hours you are expected to give your all and not limit yourself in anyway and behave in a more professional or sophisticated manner much like if they were going to an actual 9 – 5 job this behavior is expected from them. Indeed, while wearing a school uniform does not allow for self-expression some think that students should make choices in regards to life based on their own personal values instead of the precedent and governance chosen for them and this is important for their own well-being and development as they con tinue to grow up. Anderson (2002) states, â€Å"four basic reasons for promoting school uniforms: 1) enhanced school safety, 2) improved learning climate, 3) higher self-esteem for students, and 4) less stress on the family.† Uniforms are a good idea as it causes students to focus on their academics and learning rather than on latest fashions or what the next student is wearing because  wearing uniforms helps students get prepared and ready to learn and it reminds them that certain level of respect is required of them towards their instructors, themselves and the other students. The use and purchase of uniforms can also improve Schools should provide a safe environment for learning. Wearing uniforms could be considered a form of good discipline and causing students to learn and adhere to rules. Calling for uniforms in schools can reduce violence and propel our students into a better category academically in the world as a whole. The wearing of a school uniform may not resolve all or any of the problems that occur day to day in our schools now but there are some other benefits to wearing them and those benefits should be taken into account. (Lester 106-12) With classrooms today needing a more respect for teachers and each other wearing school uniforms can help with that. Conformity should be painless with uniforms being incorporated in our education system, as the guidelines are definite and straightforward. References Anderson, W. (2002). School Dress Codes and Uniform Policies. Policy Report. Washington, D.C.: Office of Educational Research and Improvement. ERIC document ED 471 528. Huss, J. A. (2007). The Role of School Uniforms in Creating an Academically Motivating Climate: Do Uniforms Influence Teacher Expectations? Journal of Ethnographic & Qualitative Research, 131-39. King, K.A. (1998, January). Should school uniforms be mandated in elementary school? Journal of School Health. p. 32. Murray, R. K. (1997). The Impact of School Uniforms on School Climate. NASSP Bulletin, 81(593), 106-12. Wade, K., & Stafford, M. E. (2003). Public School Uniforms: Effect on Perceptions of Gangs Presence, School Climate, and Student Self-Perceptions. Education and Urban Society, 35 (4), 399-420. Walmsley, A. (2011). What the United Kingdom Can Teach the United States About School Uniforms. Phi Delta Kappan, 92(6), 63-66.